HIPPI, short for High Performance Parallel Interface, is a computer bus for the attachment of high speed storage devices to supercomputers, in a point-to-point link. It was popular in the late 1980s and into the mid-to-late 1990s, but has since been replaced by ever-faster standard interfaces like Fibre Channel and 10 Gigabit Ethernet.

The first HIPPI standard defined a 50-pair (100-wire) twisted pair cable, running at 800 Mbit/s (100 MB/s) with maximum range limited to 25 metres (82 ft), but was soon upgraded to include a 1600 Mbit/s (200 MB/s) mode running on Serial HIPPI fibre optic cable with a maximum range of 10 kilometres (6.2 mi).

HIPPI usage dwindled in the late 1990s. This was partly because Ultra3 SCSI offered rates of 320 MB/s and was available at almost any computer store at commodity prices. Meanwhile, Fibre Channel offered simple interconnect with both HIPPI and SCSI (it can run both protocols) and speeds of up to 400 MB/s on fibre and 100 MB/s on a single pair of twisted pair copper wires. Both of these systems have since been supplanted by even higher performance systems during the 2000s.